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平成20年度分子創薬化学セミナー(前期)
 平成20年度分子創薬化学セミナー(前期)

第63回(2008. 09. 20)
担当者:時實梨衣
文献名:"Lewis Acid-Catalyzed Intermolecular [4 + 2] Cycloaddition of 3-Alkoxycyclobutanones to Aldehydes and Ketones"
J. Matsuo, S. Sasaki, H. Tanaka, and H. Ishibashi
J. Am. Chem. Soc., 130 (35), 11600-11601 (2008).

第62回(2008. 09. 20)
担当者:森本晃允
文献名:"Pallasium-Catalyzed C-H Functionalization of Pyridine N-Oxides: Highly Selective Alkenylation and Direct Arylation with Unactivated Arenes"
S. H.Cho, S. J. Hwang, and S. Chang
J. Am. Chem. Soc., 130 (29), 9254-9256 (2008).


第61回(2008. 09. 13)
担当者:山下大輔
文献名:"Orthogonal Pd- and Cu-Based Catalyst Systems for C- and N-Arylation of Oxindoles"
R. A. Altman, A. M. Hyde, X. Huang, and S. L. Buchwald
J. Am. Chem. Soc., 130 (29), 9613-9620 (2008).

第60回(2008. 09. 13)
担当者:七瀧浩志
文献名:"Catalytic C-H Amination for the Preparation of Substituted 1,2-Diamines"
D. E. Olson and J. D. Bois
J. Am. Chem. Soc., 130 (34), 11248-11249 (2008).

第59回(2008. 09. 13)
担当者:折戸太一
文献名:"Dehydrogenative Cyclocondensation of Aldehydes, Alkynes, and Dialkylsilanes"
R. D. Baxter and J. Montgomery
J. Am. Chem. Soc., 130 (30), 9662-9663 (2008).


第58回(2008. 07. 26)
担当者:上野麻衣
文献名:"Asymmetric Total Synthesis of (-)-Quinocarcin"
Y.-C. Wu, M. Liron, and J. Zhu
J. Am. Chem. Soc., 130 (22), 7148-7152 (2008).

第57回(2008. 07. 26)
担当者:矢野哲平
文献名:"1-Acetyl-2,3-dimethylimidazolidine: A Novel Organic Reductant for Transfer Hydrogenation"
D. Li, Y. Zhang, G. Zhou, and W. Guo
Synlett, (2), 225-228 (2008).

第56回(2008. 07. 26)
担当者:坂井亮介
文献名:"Enantioselective Synthesis of 2-Substituted Alcohols Using (+)-(1S,2S)-Pseudoephedrine as Chiral Auxiliary"
L. F. Tietze, C. Raith, C. C. Brazel, S. Holsken, and J. Magull
Synthesis, (2), 229-236 (2008).


第55回(2008. 07. 19)
担当者:岡崎真治
文献名:"1,3-Diol Synthesis via Controlled, Radical-Mediated C-H Functionalization"
K. Chen, J. M. Richter, and P. S. Baran
J. Am. Chem. Soc., 130 (23), 7247-7249 (2008).

第54回(2008. 07. 19)
担当者:久次米永子
文献名:"Activation of N-Sulfonyl Oxaziridines Using Copper(II) Catalysts: Aminohydroxylation of Styrenes and 1,3-Dienes"
D. J. Michaelis, M. A. Ischay, and T. P. Yoon
J. Am. Chem. Soc., 130 (20), 6610-6615 (2008).

第53回(2008. 07. 19)
担当者:丸木あゆみ
文献名:"Selective Synthesis of Diastereomeric Fluorinated Octadeca-2,4-dienoates and Octadeca-2,4-dien-1-ols"
G. S. Nikolova and G. Haufe
Synthesis, (4), 527-536 (2008).


第52回(2008. 07. 12)
担当者:廣山裕太
文献名:"Acetylation of N-Heteroaryl Bromides via PdCl2/(o-tolyl)3P Catalyzed Heck Reactions"
T. He, X. Tao, X. Wu, L. Cai, and V. W. Pike
Synthesis, (6), 887-890 (2008).

第51回(2008. 07. 12)
担当者:中山ゆかり
文献名:"Nonenzymatic Kinetic Resolution of Amines in Ionic Liquids"
C. Sabot, P. V. Subhash, A. Valleix, S. Arseniyadis, and C. Mioskowski
Synlett, (2), 268-272 (2008).


第50回(2008. 07. 05)
担当者:竹安正範
文献名:"Catalytic Asymmetric Alkylations of Ketoimines. Enantioselective Synthesis of N-Substituted Quaternary Carbon Stereogenic Centers by Zr-Catalyzed Additions of Dialkylzinc Reagents to Aryl-, Alkyl-, and Trifluoroalkyl-Substituted Ketoimines"
P. Fu, M. L. Snapper, and A. H. Hoveyda
J. Am. Chem. Soc., 130 (16), 5530-5541 (2008).


第49回(2008. 06. 28)
担当者:嘉村真法
文献名:"Heck Reactions of Crotonaldehyde"
M. Stadler and B. List
Synlett, (4), 597-599 (2008).


第48回(2008. 06. 14)
担当者:大勢祐希子
文献名:"Asymmetric Hydrogenation of Di and Trisubstituted Enol Phosphinates with N,P-Ligated Iridium Complexes"
P. Cheruku, J. Diesen, and P. G. Andersson
J. Am. Chem. Soc., 130 (16), 5595-5599 (2008).

第47回(2008. 06. 14)
担当者:時實梨衣
文献名:"Enantioselective Synthesis of P-Stereogenic Alkynylphosphine Oxides by Rh-Catalyzed [2+2+2] Cycloaddition"
G. Nishida, K. Noguchi, M. Hirano, and K. Tanaka
Angew. Chem. Int. Ed, 47 (18), 3410-3413 (2008).


第46回(2008. 06. 07)
担当者:市川喬士
文献名:"Tandem Rh(I)-Catalyzed [(5+2)+1] Cycloaddition/Aldol Reaction for the Construction of Linear Triquinane Skeleton: Total Syntheses of (±)-Hirsutene and (±)-1-Desoxyhypnophiln"
J. Jiao, C. Yuan, and Z.-X. Yu
J. Am. Chem. Soc., 130 (13), 4421-4430 (2008).

第45回(2008. 06. 07)
担当者:森本晃允
文献名:"Powdered KOH in DMSO: An Efficient Base for Asymmetric Cyclization via Memory of Chirality at Ambient Temperature"
T. Kawabata, K. Moriyama, S. Kawakami, and K. Tsubaki
J. Am. Chem. Soc., 130 (12), 4153-41574 (2008).


第44回(2008. 05. 24)
担当者:津村武史
文献名:"Generation and Tandem Reactions of 1-Alkenyl-1,1-Heterobimetallics: Practical and Versatile Reagents for Organic Synthesis"
H. Li, P. J. Carroll, and P. J. Walsh
J. Am. Chem. Soc., 130 (11), 3521-3531 (2008).

第43回(2008. 05. 24)
担当者:七瀧浩志
文献名:"Addition/Oxidative Rearrangement of 3-Furfurals and 3-Furyl Imines: New Approaches to Substituted Furans and Pyrroles"
A. R. Kelly, M. H. Kerrigan, and P. J. Walsh
J. Am. Chem. Soc., 130 (12), 4097-4104 (2008).


第42回(2008. 05. 10)
担当者:中尾允泰
文献名:"Asymmetric Ni-Catalyzed Conjugate Allylation of Activated Enones"
J. D. Sieber and J. P. Morken
J. Am. Chem. Soc., 130 (14), 4978-4983 (2008).

第41回(2008. 05. 10)
担当者:折戸太一
文献名:"Nucleophilic β-Oniovinylation: Concept, Mechanism, Scope, and Applications"
R. Weiss, M. Bess, S. M. Huber, and F. W. Heinemann
J. Am. Chem. Soc., 130 (14), 4610-4617 (2008).

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